BRC-GAB Seminar: Marcus Munafò, “The CHRNA5-A3-B4 gene cluster: More than just smoking quantity?”

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Date(s) - 22/01/2015
4:30 pm - 5:30 pm

SGDP Seminar Room


Marcus Munafò
Professor of Biological Psychology, UK Centre for Tobacco and Alcohol Studies, University of Bristol

The CHRNA5-A3-B4 is robustly associated with smoking quantity among smokers. However, evidence is emerging that this association is considerably stronger when precise biomarker phenotypes of smoking quantity are used. Variants in this region may also be associated with other smoking behaviour phenotypes. Intriguingly, there is also emerging evidence that these variants may also be associated with phenotypes as diverse as body mass index and schizophrenia.

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