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  • Upcoming papers - (submitted, accepted or ahead or print) +

    • Honghan Wu, Anika Oellrich, Christine Girges, Bernard de Bono, Tim Hubbard, and Richard Dobson. Automated PDF highlights to support faster curation of literature on Parkinson's and Alzheimer's disease. Submitted to Database (Virtual Issue for BioCuration 2017).
    • Trajectories of Dementia-related Cognitive Decline in a large Mental Health Records Derived Patient Cohort. Elizabeth Baker, Ehtesham Iqbal, Caroline Johnston, Matthew Broadbent, Hitesh Shetty, Robert Stewart, Robert Howard, Stephen Newhouse, Mizanur Khondoker and Richard Dobson. Submitted to PLOS Medicine, Special issue: "Dementia across the lifespan and around the globe—Pathophysiology, prevention, treatment, and societal impact", September 2016.
    • Mining Social Media as a Means to Study the Consequences of Dementia Diagnoses on Carers and Relatives. Anika Oellrich, George Gkotsis, Rina Dutta, Richard Dobson and Tim Hubbard. Submitted to PLOS Medicine, Special issue: "Dementia across the lifespan and around the globe—Pathophysiology, prevention, treatment, and societal impact", September 2016.
    • Empirical feature selection in biomarker discovery: DKK1 overexpression in vitro nominates proteins predicting Alzheimer’s in blood. Ben Lui, Richard Dobson. Submitted to Translational Psychiatry
    • Brain transcriptome sequencing of a natural model of Alzheimer's disease. Patricia Cogram, Francisco Altimiras; Barbara Uszczynska-Ratajczak; Leandro Farias; Francisco Camara; Anna Vlasova; Emilio Palumbo; Stephen Newhouse; Robert Deacon; David E Loyola; Michael J Hurley; Rodrigo A Vasquez; Richard Dobson; Roderic Guigó. Submitted to Alzheimer's & Dementia
    • Antidepressant drug-specific prediction of depression treatment outcomes from genetic and clinical variables. Raquel Iniesta, Karen Hodgson, Daniel Stahl PhD, Karim Malki, Wolfgang Maier, Marcella Rietschel, Ole Mors, Joanna Hauser, Neven Henigsberg, Mojca Zvezdana Dernovsek, Daniel, Souery, Richard Dobson, Katherine J. Aitchison, Anne Farmer, Peter McGuffin, Cathryn M. Lewis, Rudolf Uher. Submitted to Biological Psychiatry
    • Health­-record Embedded Comparative Effectiveness Trials: a Case for Employing Multi­agent Systems. Zina Ibrahim , Steven J Kiddle , Honghan Wu , Maximilian Kerz, Yevgenyia Kovalchuk, Simon Miles2 and Richard Dobson1 Submitted to BMC Medical Informatics and Decision Making.
    • Association of blood lipids with Alzheimer's Disease: a comprehensive lipidomics analysis. P Proitsi, M Kim, L Whiley, Simmons A, M Sattlecker, L Velayudhan, MK Lupton, H Soininen, I Kloszewska, P Mecocci, M Tsolaki, B Vellas, S Lovestone, JF Powell, RJB 
Dobson, and C Legido-Quigley. Accepted by Alzheimer's and Dementia.
    • Gene expression analysis in peripheral blood of first episode psychosis patients. Daniel J Leirer, Conrad O Iyegbe, Marta Di Forti, Hamel Patel, Elena Carra, Sara Fraietta, Marco Colizzi, Valeria Mondelli, Diego Quattrone, John Lally, Olesya Ajnakina, Sang Hyuck Lee, Charles J Curtis, Gerome Breen, Carmine Pariente, Katherine Aitchison, Paola Dazzan, Robin M Murray, Richard J B Dobson and Stephen J Newhouse. Submitted to Biological Psychiatry, August 2016
    • ADEPt, A Semantically Enriched Information Extraction Pipeline from Free-text Electronic Health Records: the Case of Adverse Drug Events. Ehtesham Iqbal, Daniel Rhodes, Honghan Wu, Robbie Mallah, Alvin Romero, Matthew Broadbent, Robert Stewart, Richard Dobson, Zina Ibrahim. Submitted to the Journal of the Association for Information Science and Technology, Special Issue on Biomedical Information Retrieval, August 2016.
    • Does genetic risk help to predict amyloid burden in a non-demented population? A Bayesian approach. Nicola Voyle, Willemijn Jansen, Aoife Keohane, Hamel Patel, Amos Folarin, Stephen Newhouse, Caroline Johnston, Kuang Lin, Pieter Jelle Visser, Angela Hodges, Richard JB Dobson and Steven J Kiddle for the Alzheimer's Disease Neuroimaging Initiative. Submitted to PLoS Medicine, September 2016.
    • Genetic risk and plasma tau as markers of amyloid-beta and tau burden in cerebrospinal fluid. Nicola Voyle, Hamel Patel, Amos Folarin, Stephen Newhouse, Caroline Johnston, Pieter Jelle Visser, Richard JB Dobson and Steven J Kiddle for the Alzheimer's Disease Neuroimaging Initiative. Accepted for publication in the Journal of Alzheimer's Disease, September 2016.
    • Challenges and Opportunities for system biology standards and tools in medical research. Matthias Koenig, Anika Oellrich, Dagmar Waltemath, Richard Dobson, Tim Hubbard and Olaf Wolkenhauer. Ontologies and Data in Life Sciences Workshop, 2016.
    • The language of mental health problems in social media. George Gkotsis, Anika Oellrich, Tim Hubbard, Richard Dobson, Maria Liakata, Sumithra Velupillai &  Rina Dutta; Computational Linguistics and Clinical Psychology workshop at NAACL HLT 2016.
    • Don’t Let Notes Be Misunderstood: A Negation Detection Method for Assessing Risk of Suicide in Mental Health Records. George Gkotsis, Sumithra Velupillai, Anika Oellrich, Harry Dean, Maria Liakata &  Rina Dutta; Computational Linguistics and Clinical Psychology workshop at NAACL HLT 2016.
    • Evaluating multi-label annotation in scienti c articles - The Multi-CoreSC Cancer Risk Assessment (CRA) corpus. James Ravenscroft, Anika Oellrich, Shyamasree Saha & Maria Liakata; Language Resources and Evaluation Conference (LREC) 2016.
    • MASs REMAPping for Randomised Controlled Trials. Zina Ibrahim & Richard Dobson; Submitted to Agents and Multi-agent Systems (AAMAS).
    • Natural Language Processing to Extract Symptoms of Severe Mental Illness from Clinical Text: the Clinical Record Interactive Search Comprehensive Data Extraction (CRIS-CODE) Project. Richard Jackson; Rashmi Patel; Nishamali Jayatilleke; Anna Kolliakou; Ball Michael; Genevieve Gorrell; Angus Roberts; Richard Dobson; Robert Stewart. Submitted to PLOS ONE
    • Identification and Replication of Cis- and Trans-Effect Protein Quantitative Trait Loci in Ageing AdultsJennifer E. Mollon, Steven J. Kiddle, Claire J. Steves, Kerrin Small, Martina Sattlecker, Nicola Voyle, Katie Lunnon, Petra Proitsi, John Powell, Angela Hodges, Stephen Williams, Tim Spector, Iwona Kloszewska, Patrizia Mecocci, Hilkka Soininen, Magda Tsolaki, Bruno Vellas, Simon Lovestone, Richard J.B. Dobson, Stephen J Newhouse Submitted to Genome Research
    • Long-term trajectories of cognitive decline in dementia inferred from short follow-up. Kiddle, Parodi, Johnston, Wallace*, Dobson*. BioaRxiv. * Equal contributions.
  • 2016 +

    • Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease. Genevera Allen , Nicola Amoroso , Catalina Anghel , Venkat Balagurusamy , Christopher Bare , Derek Beaton , Roberto Bellotti , Dr. David Bennett , Kevin Boehme , Laura Caberlotto , Cristian Caloian , Frederick Campbell , Yu-Chuan Chang , Beibei Chen , Chien-Yu Chen , Prof. Ting-Ying Chien , Tim Clark , Sudeshna Das , Christos Davatzikos , Jieyao Deng , Donna Dillenberger , Dr. Richard Dobson , Qilin Dong , Jimit Doshi , Denise Duma , Rosangela Errico , Guray Erus , Evan Everett , David Fardo , Stephen Friend , Holger Fröhlich , Jessica Gan , Dr. Peter St George-Hyslop , Dr. Satrajit Ghosh , Enrico Glaab , Dr. Robert Green , Prof. Yuanfang Guan , Ming-Yi Hong , Chao Huang , Jinseub Hwang , Joseph Ibrahim , Paolo Inglese , Qijia Jiang , Yurik Katsumata , Jo Kauwe , Arno Klein , Dehan Kong , Dr. Roland Krause , Emilie Lalonde , Mari Lauria , Eunjee Lee , Xihui Lin , Zhandong Liu , Julie Livingstone , Benjami Logsdon , Dr. Simon Lovestone , Miss Anandhi Iyappan , Tsung-wei Ma , Ashutos Malhotra , Taylor Maxwell , Emily Merrill , John Nagorski , Aishwarya Namasivayam , Manjari Narayan , Ms. Mufassra Naz , Elias Chaibub Neto , Dr. Stephen Newhouse , Thea Norman , Dr. Ramil Nurtdinov , Yen-Jen Oyang , Dr. Paul Boutros , Yudi Pawitan , Shengwen Peng , Mette Peters , Stephen Piccolo , Paurush Praveen , Dr. Corrado Priami , Veronica Sabelnykova , Philipp Senger , Xia Shen , Dr. Andrew Simmons , Aristeidis Sotiras , Gustavo Stolovitzky , Sabina Tangaro , Andrea Tateo , Yi-An Tung , Nicholas Tustison , Mr. Erdem Varol , George Vradenburg , Prof. Michael Weiner , Guanghua Xiao , Lei Xie , Prof. Yang Xie , Jia Xu , Dr. Hojin Yang , Xiaowei Zhan , Yunyun Zhou , Fan Zhu , Hongtu Zhu , Shanfeng Zhu. Nature Neuroscience (2016)
    • A novel automated high-content analysis pipeline capturing cell population dynamics from induced pluripotent stem cells live imaging data. Maximilian Kerz; Amos Folarin; Ruta Meleckyte; Richard Dobson; Fiona Watt; Davide Danovi; Journal of Biomolecular Screening (2016)
    • Complement Biomarkers as predictors of disease progression in Alzheimer’s disease. Svetlana Hakobyana, Katherine Hardingb, Mohammed Aiyazc, Richard Dobsonc, Alison Bairdd, Benjamine Liud, Claire Louise Harrisa, Simon Lovestoned and Bryan Paul Morgana,*  Journal of Alzheimer’s Disease (2016)
    • Encoding Medication Episodes for Adverse Drug Event Prediction. Honghan Wu,  Zina M. Ibrahim, Ehtesham Iqbal and Richard Dobson. Accepted to the Conference of Specialist Group in Artificial Intelligence, 2016.
    • Towards Category-Driven Rule Association Mining. Zina Ibrahim, Honghan Wu, Robbie Mallah, and Richard Dobson. Accepted to the Conference of Specialist Group in Artificial Intelligence, 2016.
    • Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis. Fogh, I. , Lin, K. , Tiloca, C. , Rooney, J. , Gellera, C. , Diekstra, F. P. , Ratti, A. , Shatunov, A. , van Es, M. A. , Proitsi, P. , Jones, A. , Sproviero, W. , Chiò, A. , McLaughlin, R. L. , Sorarù, G. , Corrado, L. , Stahl, D. , Del Bo, R. , Cereda, C. , Castellotti, B.  & 29 others 31 May 2016 In : JAMA Neurology.
    • Microduplications at the pseudoautosomal SHOX locus in autism spectrum disorders and related neurodevelopmental conditions. Tropeano, M. , Howley, D. M. , Gazzellone, M. J. , Wilson, C. E. , Ahn, J. , Stavropoulos, D. J. , Murphy, C. M. , Eis, P. S. , Hatchwell, E. , Dobson, R. J. B. , Robertson, D. , Holder, M. , Irving, M. , Nehammer, A. , Josifova, D. , Nehammer, A. , Ryten, M. , Spain, D. , Pitts, M. , Bramham, J.  & 10 others 12 Apr 2016 In : Journal of Medical Genetics.
    • Fogh I, Lin K, Tiloca C,...Newhouse S, Dobson R et al. Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis. JAMA Neurol. Published online May 31, 2016.
    • Cross Disorder Gene Expression Analysis Reveals Overlapping Immune Signatures and Disorder Specific Patterns. Simone de Jong; Stephen Newhouse; Hamel Patel; Sanghuck Lee; David Dempster; Charles Curtis; Jose Paya-Cano; Declan Murphy; C Wilson; Jamie Horder; M Mendez; Philip Asherson; Margarita Rivera; Helen Costello; Stefanos Maltezos; Susannah Whitwell; Mark Pitts; Charlotte Tye; Karen Ashwood; Patrick Bolton; Sarah Curran; Peter McGuffin; Richard Dobson; Gerome Breen.  British Journal of Psychiatry,  2016 May 5. pii: bjp.bp.115.175471. [Epub ahead of print]
    • Combining clinical variables to optimize prediction of antidepressant treatment outcomes. Raquel Iniesta, Karim Malki, Wolfgang Maier, Marcella Rietschel, Ole Mors, Joanna Hauser, Neven Henigsberg , Mojca Zvezdana Dernovsek , Daniel Souery , Daniel Stahl , Richard Dobson , Katherine J. Aitchison , Anne Farmer , Cathryn M. Lewis , Peter McGuffin and Rudolf Uher. Journal of Psychiatric Research. DOI: 10.1016/j.jpsychires.2016.03.016 Date accepted: 30th March 2016
    • Blood metabolite markers of Neocortical Amyloid Burden: Discovery and enrichment using candidate proteins. Nicola Voyle, Min Kim, Petroula Proitsi, Nicholas J Ashton, Alison L Baird, Chantal Bazenet, Abdul Hye, Sarah Westwood, Raymond Chung, Malcolm Ward, Gil D Rabinovici, Simon Lovestone, Gerome Breen, Cristina Legido-Quigley, Richard JB Dobson and Steven J Kiddle. Translational Psychiatry (2016) 6, e719; doi:10.1038/tp.2015.205. Published online 26 January 2016
    • Alzheimer's Disease: are blood and brain markers related? A systematic review. Khan, Dobson, Sattlecker* and Kiddle*. Annals of Clinical and Translational Neurology (Advance access). * Equal contributions.
  • 2015 +

    • A Multi-Agent Platform for Automating the Collection of Patient-Provided Clinical Feedback. Zina Ibrahim, Argyris Stringaris, Richard Dobson. The International Conference on Autonomous Agents and Multi Agent Platforms, pp. 831-839, 2015
    • Longitudinal protein changes in blood plasma associated with the rate of cognitive decline in Alzheimer’s disease. Martina Sattlecker, Mizan Khondoker, Petroula Proitsi, Stephen Williams, Hilkka Soininen, Iwona Kłoszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Simon Lovestone, and Richard JB Dobson. Journal of Alzheimer's Disease. 2015 Nov 23. PMID: 26599049. 
    • Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer's disease. Petroula Proitsi, Min Kim, Luke Whiley, Megan Pritchard, Hilkka Soininen, Iwona Kloszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Pak Sham, Simon Lovestone, John F Powell* , Richard JB Dobson*, and Cristina Legido-Quigley*. * Equal contributions. Translational Psychiatry. 2015 Jan 13;5:e494. doi: 10.1038/tp.2014.127.
    • Transcriptomics and the mechanisms of antidepressant efficacy. Karen Hodgson, Dr. Katherine Tansey , Dr. Timothy Powell , Dr. Giovanni Coppola , Dr. Rudolf Uher , Dr. Mojca Zvezdana Dernovšek , Dr. Ole Mors , Prof. Jonanna Hauser , Dr. Daniel Souery , Prof. Wolfgang Maier , Dr. Neven Henigsberg , Prof. Marcella Rietschel , Prof. Anna Placentino , Prof. Katherine Aitchison , Prof. Ian W Craig , Prof. Anne Farmer , Dr. Gerome Breen , Prof. Peter McGuffin , Dr. Richard Dobson. European Neuropsychopharmacology 2015 Nov 12. pii: S0924-977X(15)00334-X. doi: 10.1016/j.euroneuro.2015.10.009. [Epub ahead of print]
    • Identification of adverse drug events from free text electronic patient records and Information in a Large Mental Health Case Register. Robbie Mallah, Ehtesham Iqbal, Richard George Jackson, Michael Ball, Matthew Broadbent, Olubanke Dzahini1, Robert Stewart, Caroline Johnston, Richard JB Dobson. PLoS One. 2015; 10(8): e0134208.
    • A pathway based classification method for analysing gene expression for Alzheimer's Disease diagnosis. Nicola Voyle, Aoife Keohane, Stephen Newhouse, Katie Lunnon, Caroline Johnston, Hilkka Soininen, Iwona Kloszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Simon Lovestone on behalf of the AddNeuroMed consortium, Angela Hodges, Steven Kiddle and Richard JB Dobson. Journal of Alzheimer's Disease. 2015 Oct 15;49(3):659-69. doi: 10.3233/JAD-150440.
    • NGSeasy: a next generation sequencing pipeline in Docker containers. (2015) Amos Folarin, Richard Dobson, Stephen Newhouse. [version 1; referees: 3 approved with reservations] F1000Research 2015, 4:997
    • Quality control, imputation and analysis of genome-wide genotyping data from the Illumina HumanCoreExome microarray. Jonathan R.I. Coleman, Jack Euesden, Hamel Patel 1, Stephen Newhouse, Amos Folarin, Paul O'Reilly, Cathryn Lewis, Gerome Breen. Brief Funct Genomics. (2015) Oct 5. pii: elv037. [Epub ahead of print]
    • Cannabis use and treatment resistance in first episode psychosis: a natural language processing study. Patel, Rashmi, Robin Wilson, Richard Jackson, Michael Ball, Hitesh Shetty, Matthew Broadbent, Robert Stewart, Philip McGuire, and Sagnik Bhattacharyya.  The Lancet 385 (2015): S79.
    • Delays before Diagnosis and Initiation of Treatment in Patients Presenting to Mental Health Services with Bipolar Disorder. Patel, Rashmi, Hitesh Shetty, Richard Jackson, Matthew Broadbent, Robert Stewart, Jane Boydell, Philip McGuire, and Matthew Taylor. (2015): PLOS ONE e0126530.
    • Mood instability is a common feature of mental health disorders and is associated with poor clinical outcomes. Patel, Rashmi, Theodore Lloyd, Richard Jackson, Michael Ball, Hitesh Shetty, Matthew Broadbent, John R. Geddes, Robert Stewart, Philip McGuire, and Matthew Taylor. BMJ open 5, no. 5 (2015): e007504.
    • Bai Y, Dai X, Harrison A, Johnston C, Chen M. Toward a next-generation atlas of RNA secondary structure. Briefings in bioinformatics. 17(1):63-77. 2016. [pubmed]
    • Microdeletions of ELP4 are associated with language impairment, autism spectrum disorder and epilepsy Pal, D. , Addis, L. , Ahn, J. W. , Dobson, R. , Dixit, A. , Ogilvie, C. , Pinto, D. , Vaags, A. K. , Coon, H. , Chaste, P. , Wilson, S. , Parr, J. R. , Andrieux, J. , lenne, B. , turner, Z. , leuzzi, V. , aubell, K. , koillinen, H. , Curran, S. , Marshall, C. R. , Scherer, S. W. & 1 others 2015 In : Human Mutation, 2015.
    • No evidence to suggest that the use of acetylcholinesterase inhibitors confounds the results of two blood-based biomarker studies in Alzheimer’s disease. Justin Tao Wen Chiam, Katie Lunnon, Nicola Voyle, Petroula Proitsi, Giovanni Coppola, Daniel Geschwind, Sally Nelson, Caroline Johnston, Hilkka Soininen, Iwona Kłoszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas,  Angela Hodges, Simon Lovestone, Stephen Newhouse, Richard James Butler Dobson, Steven John Kiddle, Martina Sattlecker. Accepted at Journal of Alzheimer’s Disease.
    • Plasma protein biomarkers of Alzheimer’s disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes. Steven Kiddle, Claire Steves, Mitul Mehta, Andrew Simmons, Xiaohui Xu, Stephen Newhouse, Martina Sattlecker, Nicholas  Ashton, Chantal Bazenet, Richard Killick, Jihad Adnan, Eric Westman, Sally Nelson, Hilkka Soininen, Iwona Kloszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Charles Curtis, Gerome Breen, Steven Williams, Simon Lovestone, Tim Spector, and Richard Dobson. Translational Psychiatry (link)
    • CohortExplorer: A generic application programming interface (API) for entity attribute value database schemas. Abhishek Dixit and Richard Dobson. Accepted at JMIR
    • TextHunter – A User Friendly Tool for Extracting Generic Concepts from Free Text in Epidemiological Research. Richard Jackson, Michael Ball, Rashmi Patel, Richard D. Hayes, Richard Dobson, Robert Stewart. Accepted as a paper at AMIA 2014
    •  Blood protein predictors of brain amyloid for enrichment in clinical trials?  Ashton*, Kiddle*, Graf, Ward, Baird, Hye, Westwood, Wong, Dobson, Rabinovici, Miller, Rosen, Torres, Zhang, Thurfjell, Covin, Hehir, Baker, Bazenet, Lovestone, AIBL. Alzheimer’s and Dementia: Diagnosis, Assessment and Disease Monitoring (2015). (link)
    • Linking genetics of brain changes to Alzheimer’s disease: sparse whole genome association scan of regional MRI volumes in the ADNI and AddNeuroMed cohorts. Mizanur Khondoker, Stephen Newhouse, Eric Westman, J-Sebastian Muehlboeck, Patrizia Mecocci, Bruno Vellas, Magda Tsolaki, Iwona Kłoszewska, Hilkka Soininen, Simon Lovestone, Richard Dobson* and Andrew Simmons*. * Equal Contributions. Accepted to the Journal of Alzheimer's Disease
    • Blood protein markers of Neocortical Amyloid-β Burden: A candidate study using SOMAscan technology. Nicola Voyle, David Baker, Samantha C. Burnham, Antonia Covin, Zhanpan Zhang, Dipen P. Sangurdekar, Cristina A. Tan Hehir, Chantal Bazenet, Simon Lovestone, Steven Kiddle, Richard JB. Dobson and the AIBL research group. Journal of Alzheimer’s Disease; 46 (2): 947 - 962.
    • The relative vertex clustering value - a new criterion for the fast discovery of functional modules in protein interaction networks. Zina Ibrahim and Alioune Ngom.  BMC Bioinformatics 2015, 16(Suppl 4):S3
    • Khan W, Aguilar C, Kiddle SJ. A Subset of Cerebrospinal Fluid Proteins from a Multi-Analyte Panel Associated with Brain Atrophy, Disease Classification and Prediction in Alzheimer's Disease. PloS one. 10(8):e0134368. 2015. [pubmed]
  • 2014 +

    • The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for GxE research. Iyegbe C, Campbell D, Butler A, Ajnakina O, Sham P. Soc Psychiatry Psychiatr Epidemiol. 2014 Feb;49(2):169-82. doi: 10.1007/s00127-014-0823-2. Epub 2014 Jan 17.
    • Hodgson K, Tansey KE, Uher R. Exploring the role of drug-metabolising enzymes in antidepressant side effects. Psychopharmacology. 232(14):2609-17. 2015. [pubmed]
    • Menni C, Kiddle SJ, Mangino M. Circulating Proteomic Signatures of Chronological Age. The journals of gerontology. Series A, Biological sciences and medical sciences. 70(7):809-16. 2015. [pubmed]
    • Thompson PM, Stein JL, Medland SE. The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain imaging and behavior. 8(2):153-82. 2014. [pubmed]
    • Current trends in machine learning methods applied to spectroscopic cancer diagnosis. Martina Sattlecker, Nick Stone, Conrad Bessant. TrAC Trends in Analytical Chemistry. Volume 59, July–August 2014, Pages 17–25
    • Investigation of negative symptoms in schizophrenia with a machine learning text-mining approach. Patel, Rashmi, Nishamali Jayatilleke, Richard Jackson, Robert Stewart, and Philip McGuire.  The Lancet 383 (2014): S16.
    • An Intelligent Agent-based System for the Early Discovery of Adverse Drug Reactions. Zina Ibrahim, Robbie Mallah and Richard Dobson. The Florida Artificial Intelligence Research Society Conference, 272-277, 2014.
    • TextHunter–A User Friendly Tool for Extracting Generic Concepts from Free Text in Clinical Research. Ball, Michael, Rashmi Patel, Richard D. Hayes, Richard JB Dobson, and Robert Stewart.  In AMIA Annual Symposium Proceedings, vol. 2014, p. 729. American Medical Informatics Association, 2014.
    • The effect of clozapine on premature mortality: an assessment of clinical monitoring and other potential confounders.Hayes, Richard D., Johnny Downs, Chin-Kuo Chang, Richard G. Jackson, Hitesh Shetty, Matthew Broadbent, Matthew Hotopf, and Robert Stewart.  Schizophrenia bulletin (2014): sbu120.
    • The Incidence of Sexually Dimorphic Gene Expression Varies Greatly between Tissues in the Rat. Huby, Russell DJ, Philip Glaves, and Richard Jackson.  PloS one 9, no. 12 (2014): e115792.
    • Development and evaluation of a de-identification procedure for a case register sourced from mental health electronic records.Fernandes, Andrea C., Danielle Cloete, Matthew TM Broadbent, Richard D. Hayes, Chin-Kuo Chang, Richard G. Jackson, Angus Roberts et al.   BMC medical informatics and decision making 13, no. 1 (2013): 71.
    • Alzheimer's disease biomarker discovery using SOMAscan™ multiplexed protein technology. Martina Sattlecker, Steven Kiddle, Stephen Newhouse, Petroula Proitsi, Sally Nelson, Stephen Williams, Caroline Johnston, Richard Killick, Andrew Simmons, Eric Westman, Angela Hodges, Hilkka Soininen, Iwona Kłoszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Simon Lovestone and Richard Dobson. Accepted to Alzheimer's & Dementia
    • Candidate blood proteome markers of Alzheimer's disease onset and progression: a systematic review and replication study. Steven Kiddle*, Martina Sattlecker*, Petroula Proitsi, Andrew Simmons, Chantal Bazenet, Eric Westman, Sally Nelson, David Sterling, Stephen Williams, Angela Hodges, Caroline Johnston, Hilka Soininen, Iwona Kłoszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Stephen Newhouse, Simon Lovestone, And Richard Dobson (* Joint first authors). Accepted to Journal of Alzheimer's Disease
    • A comparison of machine learning methods for classification using simulation with examples using multiple datasets from mental health studies. Mizanur Khondoker, Richard Dobson, Caroline Skirrow, Andrew Simmons and Daniel Stahl. Accepted to Statistical Methods in Medical Research
    • BBGRE: Brain & Body Genetic Resource Exchange. Accepted to DATABASE. Joo Wook Ahn, Abhishek Dixit, Caroline Johnston, Caroline Mackie Ogilvie, David A Collier, Sarah Curran and Richard Dobson
    • The Bayesian Approach to Biological Knowledge Discovery: the Gene Expression Case. International Journal of Approximate Reasoning, In Review Zina Ibrahim, Stephen Newhouse, Richard Dobson
    • Protein interaction networks associated with cardiovascular disease and cancer: shared network properties and prioritisation of candidate disease related proteins. Richard JB Dobson, Patricia B Munroe, Mark J Caulfield, Mansoor AS Saqi. Journal of Data Mining and Bioinformatics, In Press.
    • Chiam JT, Dobson RJ, Kiddle SJ, Sattlecker M. Are blood-based protein biomarkers for Alzheimer's disease also involved in other brain disorders? A systematic review. Journal of Alzheimer's disease : JAD. 43(1):303-14. 2015. [pubmed]
    • Hye A, Riddoch-Contreras J, Baird AL. Plasma proteins predict conversion to dementia from prodromal disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 10(6):799-807.e2. 2014. [pubmed]
    • Corrigan A, Walker JL, Wickramasinghe S. Pharmacogenetics of pemetrexed combination therapy in lung cancer: pathway analysis reveals novel toxicity associations. The pharmacogenomics journal. 14(5):411-7. 2014. [pubmed]
  • 2013 +

    • Burney MJ, Johnston C, Wong KY. An epigenetic signature of developmental potential in neural stem cells and early neurons. Stem cells (Dayton, Ohio). 31(9):1868-80. 2013. [pubmed]
    • Khan W, Giampietro V, Ginestet C. No differences in hippocampal volume between carriers and non-carriers of the ApoE ε4 and ε2 alleles in young healthy adolescents. Journal of Alzheimer's disease : JAD. 40(1):37-43. 2014. [pubmed]
    • Ibrahim Z, Newhouse S, Dobson R (2013) Detecting Epistasis in the Presence of Linkeage Disequilibrium: A Focused Comparison. IEEE Symposium on Computational Intelligence in Bioinformatics, pp 96-103
    • Tropeano M, Ahn JW, Dobson RJB, Breen G, Rucker J, et al. (2013) Male-Biased Autosomal Effect of 16p13.11 Copy Number Variation in Neurodevelopmental Disorders. PLoS ONE 8(4): e61365. doi:10.1371/journal.pone.0061365
    • Soldati C, Bithell A, Johnston C, Wong KY, Stanton LW, Buckley NJ. Dysregulation of REST-regulated coding and non-coding RNAs in a cellular model of Huntington's disease. Journal of neurochemistry. 124(3):418-30. 2013. [pubmed]
    • Killick R, Ribe EM, Al-Shawi R. Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway. Molecular psychiatry. 19(1):88-98. 2014. [pubmed]
    • Guo Y, Lanktree MB, Taylor KC. Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals. Human molecular genetics. 22(1):184-201. 2013. [pubmed]
    • K. Lunnon, M. Sattlecker, S.J. Furney, G. Coppola, A. Simmons, P. Proitsi, M.K. Lupton, A. Lourdusamy, C. Johnston, H. Soininen, I. Kłoszewska, P. Mecocci, M. Tsolaki, B. Vellas, D. Geschwind, S. Lovestone, R. Dobson*, A. Hodges*. , "A blood gene expression marker of early Alzheimer's disease.", Journal of Alzheimer's disease : JAD, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23042217 * Equal contributions
    • Danovi D, Folarin A, Gogolok S. A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1. PloS one. 8(10):e77053. 2013. [pubmed]
    • Wu CY, Chang CK, Robson D. Evaluation of smoking status identification using electronic health records and open-text information in a large mental health case register. PloS one. 8(9):e74262. 2013. [pubmed]
    • Finding negative symptoms of schizophrenia in patient records." Gorrell, Genevieve, Richard Jackson, Angus Roberts, and Robert Stewart. Proc NLP Med Biol Work (NLPMedBio), Recent Adv Nat Lang Process (RANLP), Hissar, Bulg (2013): 9-17.
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