NIHR Maudsley Biomedical Research Centre (BRC) Bioinformatics Core

 

Welcome to the Bioinformatics Core at the National Biomedical Research Centre and Dementia Unit (BRC/U) at South London and Maudsley NHS Foundation Trust (SLaM) and King’s College London (KCL).

Who are we?

Our research is focused on translational bioinformatics and its application to complex disease. We complement the strategic goals of the BRC/U by facilitating  the integration of clinical data from patient records with large biological datasets. The biological data involved derives from disease-focused studies of transcriptomics, genomics, epigenetics, proteomics and neuroimaging. This type of integrative approach will better serve the need to identify biomarkers of diagnosis, prognosis, progression and treatment response for neuropsychiatric disorders. Please see the BRC/U website for more background about the BRC/U

Our areas of expertise

Our group brings together a range of experience in data analysis, bioinformatics, software development, systems administration, mathematics and statistics. Our multi-disciplinary team is able to develop and implement solutions for analysing and interpreting complex integrative datasets and for communicating findings to clinicians and patients. If you are interested in a collaboration, please contact us. Also see our jobs page

Our infrastructure

As well as our contributions to data management, analysis and integration, we also provide the BRC/U with the computing infrastructure to handle their clinical and molecular diagnostic data. This includes a Linux cluster supporting a wide range of bioinformatics software and workflows.

Sharing Data
A “guide” for anyone who needs to share data with statisticians and bioinformaticians and data scientists.

Where are we?

We are based in South London, in the MRC Social, Genetic and Developmental Psychiatry Centre, at the Institute of Psychiatry in Denmark Hill. We work closely with both KCL researchers and clinicians from SLaM.